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The antibacterial effect of Endoseal TCS mixed with water-soluble mangostin derivatives of Garcinia mangostana L. ethanol extract against Enterococcus faecalis and Staphylococcus aureus

International Journal of Oral Biology 2021³â 46±Ç 1È£ p.45 ~ 50
¹ÚÅ¿µ, ÀÓÀ±°æ, ±èÁøÈñ, À̴뼺, ±¹Áß±â,
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¹ÚÅ¿µ ( Park Tae-Young ) - Chosun University School of Dentistry Department of Conservative Dentistry
ÀÓÀ±°æ ( Lim Yun-Kyong ) - Chosun University School of Dentistry Department of Oral Biochemistry
±èÁøÈñ ( Kim Jin-Hee ) - Chosun University School of Dentistry Department of Oral Biochemistry
À̴뼺 ( Lee Dae-Sung ) - Medi Bio Lab Co. Ltd.
±¹Áß±â ( Kook Joong-Ki ) - Chosun University School of Dentistry Department of Oral Biochemistry

Abstract


This study evaluated the antimicrobial activity of Endoseal TCS, an mineral trioxide aggregate-based root canal sealer, mixed with water-soluble mangostin derivatives (WsMD) of Garcinia mangostana L. (mangosteen) ethanol extract against Enterococcus faecalis and Staphylococcus aureus. The antibacterial activity of Endoseal TCS mixed with WsMD against three strains of E. faecalis and three strains of S. aureus was performed using agar diffusion test. The data showed that Endoseal TCS mixed with 0.115% WsMD had a zone of inhibition of 0.7 ¡¾ 0.2?2.4 ¡¾ 0.1 mm. The results suggest that Endoseal TCS mixed with WsMD of Garcinia mangostana L. ethanol extract is useful as a root canal sealer with antibacterial activity against E. faecalis and S. aureus .

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Endoseal TCS; Garcinia mangostana L.; Enterococcus faecalis; Staphylococcus aureus; Antibacterial effect

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